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Slowing down may help you avoid the discomfort that some people experience on GLP-1s

It's important to note that "flush-free" niacin (inositol hexanicotinate) and niacinamide do not provide the lipid-modifying benefits of nicotinic acid

They: Increase glucose-dependent insulin secretion Suppress glucagon (a hormone produced by the pancreas that raises blood sugar levels) Slow gastric (stomach) emptying Act on the brain to curb appetite and enhance satiety Common GLP-1s include semaglutide (Ozempic, Wegovy, Rybelsus), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), and others

Subcutaneous fat, the fat under the skin, is relatively benign

Anorectics, medications designed to suppress appetite, like fen-phen (serotonin releasing agent) were commercialized, but eventually withdrawn from the market (1997) after they were found to cause valvular disease and pulmonary hypertension